The effect of aerobic training on fibrinogen and blood cells in obese girls

Abstract Background and Objectives Obesity is associated with increased inflammatory factors such as fibrinogen and white blood cells. However, physically active people have lower levels of inflammatory factors. The aim of this study is to investigate the effects of eight weeks of aerobic exercise on fibrinogen level and blood cell number of  obese girls.   Materials and Methods This study was conducted as semi-experimental and subjects were divided (BMI > 30) into two groups: aerobic training (AT, 12 subject) and control (Con, 12 subject). The former group did aerobic exercises for eight weeks (four sessions a week, each session 60 min with the max heart beat 65-75%). Blood samples were taken before and after the exercise program. T-test was used to compare the groups (using SPSS-16 statistical software and the significance level of p < 0.05).   Results The results showed that aerobic exercise program had no significant effect on the fibrinogen level in the experimental (29.19 ± 2.46) and control (28.08 ± 2.59) groups and also on blood cell (p < 0/05). Osmolality was significantly reduced in the training group. Similarly, the dietary micronutrients and macronutrients analysis showed that between control and experimental groups throughout the training, there was no significant difference.   Conclusions  Eight weeks of moderate intensity aerobic exercise had no significant effect on plasma fibrinogen and blood cells in obese girls. It seems that the exercise program should be associated with weight loss and reduction of fat mass to improve inflammatory markers associated with obesity.